Specific implementations for different platforms and applications exist e.g., CrossOver, Darwine, and Bordeaux. The system this write-up is based on is OSX 10.6 (Snow Leopard), pClamp 10, and uses Winebottler 1.1.44.īy way of introduction, Wine is the general open-source solution for running Windows-based software on UNIX-like systems (for example, Linux and OSX) by providing a compatibility layer underneath the application. This is instructions to use the ClampFit from the pClamp suite for ion channel analysis on the Mac.